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Kainer
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| Joined: | Sat Jan 26th, 2008 |
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| Posts: | 22 |
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Posted: Thu Jul 24th, 2008 18:54 |
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Diagnosed as consistant with sarcoidosis in November 2007
These are the results of my lab blood draws:
Draw date: 06/03/08
Lab: Quest Diagnostics & Riddle Memorial Hosptial (Quest performed D-tests)
I began avoiding foods with vitamin D in November 2007
I have been on prednisone since November 2007; at the time of the this draw, I was in the process of weening, 5mg on the even days and 2.5mg on the odd days.
Other meds: Benicar, 40mg once daily, for hypertension
I had taken various supplements for several year priors to stopping in November 2007, namely fish oil and B complex.
25D Results: 15 ng/mL
1,25D Results: 56 pg/mL
Other Results:
Creatinine 1.10 mg/dL
Alk. Phosphates 65 U/L
BUN 14 mg/dL
Potassium 4.10 mmol/L
Since these preliminary tests I have had others, which I can supply if you deem that to be worthwhile.
Thanks for assistance.
JGK
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P.Bear R.N.
Research Staff
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Posted: Fri Jul 25th, 2008 20:39 |
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JGK,
Your 1,25-D is elevated at 56pg/ml (the population average is 25-29 pg/ml). It is 2.84 sigma high and based on population studies, 99.75% of the population would be expected to have a lower number. Prednisone lowers 1,25-D by 25-40% so you can see your actual level of the active hormone known as vitamin D would be even higher without this immunosuppressant.
Your 1,25-D is above the maximum of 45pg/ml listed in the Merck Manual of Diagnosis and Therapy (15 Oct 2006 online). At levels above about 42 pg/ml, the 1,25-D (generated by the Th1 inflammation) begins to stimulate bone osteoclasts, causing bone to be resorbed (dissolved) back into the bloodstream. Not only does this lead to osteoporosis, but also to calcium being deposited into soft tissue of the body, including the lungs, breasts, and the kidneys (where it forms kidney stones). Please see Osteoporosis, osteopenia and Th1 illness.
Without the prednisone your 1,25-D would have been at the level that one would suspect inflammation in major organs such as heart, liver and lungs.
When should I be concerned about cardiac symptoms?
Your 25-D of 15 ng/ml is still higher than what we like to fully enable immune system. Because 25-D is immunosuppressive, you need to avoid ALL sources of Vitamin D to get it down to a therapeutic level of 12ng/ml or less. Please see Foods To Avoid and The importance of avoiding vitamin D.
"The 25-D seems to be the most critical factor as to whether the immune system is able to start working. Any level of 25-D above about 20ng/ml is likely to be acting as an immunosuppressant, with an action very similar to that of corticosteroids." Dr. Trevor Marshall, Ph.D.
Your other posted labs are normal.
Your D-tests, diagnosis and symptoms indicate Th1 inflammation. Please see Symptoms of Hypervitaminosis-D and you may recognize a few more. You will not get well and your health will continue to deteriorate if you don't treat the underlying bacterial cause of Th1 inflammation with the MP. Please see Is the MP an applicable treatment for my disease?
Most supplements and many medications must be avoided on the MP.
Our clinical study is temporarily closed to enrollment. As vacancies occur, we will admit subjects based on an application. To obtain an application forum, please send an email to marshallprotocol2@yahoo.com with 'request MP application' in the subject line.
best, P.B.
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