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tjsmom2
Member
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Posted: Mon Jul 21st, 2008 18:25 |
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We had TJ's D levels checked again - he is pre-MP, 14years old DX CFIDS 3/07 - initial levels posted with signature line on MP site. No ingestion of high Vitamin D foods, no Vitamin D supplements, very limited sun exposure since 3/07 - TJ had a pretty good school year - a few flares, but overall symptoms were minimal, so I was surprised at the new levels: 7/10/08 25D=12. 1,25D=44. Lab used was PAML (local in our city), Doctor assured that protocol was followed for test - frozen etc.
Was I off in thinking/hoping for a lower 1,25D reading? Should we retest in case of lab error?
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I am Kim, TJ's mom - TJ was DX in 3/07 with CFIDS. Posts on the MP site from that year. TJ is PRE-MP, his doc will NOT prescribe Benicar at this point - TJ is 14 years old. DX vitaminD levels 25D=11. 1,25D=34. Latest levels 7/10/08 25D=12. 1.25D=44 ESR=9
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P.Bear R.N.
Research Staff
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Posted: Tue Jul 22nd, 2008 01:38 |
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T.J.'s Mom,
There is every possibility that T.J.'s first 1,25-D level was not properly handled or run correctly. With lab facilities we are less familiar with this is a common occurrence so even the current level of 44pg/ml could also be in error low. One could not in any case always expect a lower level of 1,25-D just from staying out of the sun alone since the inflammation will continue without the full MP treatment course; and levels can vary throughout the day. I will give you analysis of current results as if they were correct.
Your son's 1,25-D is elevated at 44pg/ml (the population average is 25-29 pg/ml). It is 1.58 sigma high and based on population studies, 94.30 % of the population would be expected to have a lower number.
1,25-D is near the maximum of 45pg/ml listed in the Merck Manual of Diagnosis and Therapy (15 Oct 2006 online). At levels above about 42 pg/ml, the 1,25-D (generated by the Th1 inflammation) begins to stimulate bone osteoclasts, causing bone to be resorbed (dissolved) back into the bloodstream. Not only does this lead to osteoporosis, but also to calcium being deposited into soft tissue of the body, including the lungs, breasts, and the kidneys (where it forms kidney stones). Please see Osteoporosis, osteopenia and Th1 illness.
25-D of 12 ng/ml would be expected to have fallen more if there were adequate sun and D protection the past months. I might look at hidden food source if he has been very careful. Because 25-D is immunosuppressive, your son still needs to avoid ALL sources of Vitamin D. Please see Foods To Avoid and The importance of avoiding vitamin D.
"The 25-D seems to be the most critical factor as to whether the immune system is able to start working. Any level of 25-D above about 20ng/ml is likely to be acting as an immunosuppressant, with an action very similar to that of corticosteroids." Dr. Trevor Marshall, Ph.D.
The D ratio is 3.66 . Any elevation above 2 suggests Th1 inflammation and that the Marshall Protocol (MP) is the correct treatment.
There is no reason to spend the extra money in case of lab error; as his numbers show TH1 inflammation and that the MP should work.
Waiting will only let the bacteria continue to grow.
Your son's D-tests, diagnosis and symptoms indicate Th1 inflammation. Please see Symptoms of Hypervitaminosis-D and you may recognize a few more. You will not get well and your health will continue to deteriorate if you don't treat the underlying bacterial cause of Th1 inflammation with the MP. Please see Is the MP an applicable treatment for my disease?
Most supplements and many medications must be avoided on the MP.
Our clinical study is temporarily closed to enrollment. As vacancies occur, we will admit subjects based on an application. To obtain an application forum, please send an email to marshallprotocol2@yahoo.com with 'request MP application' in the subject line.
best, P.B.
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Nothing contained in this site is or should be considered, or used as a substitute for, medical advice, diagnosis or treatment by your physician.
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