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Den
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Joined: Tue Dec 11th, 2007
Location: Sydney, Australia
Posts: 16
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 Posted: Wed Dec 12th, 2007 04:41

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Hi all,
I have been a member of sarcoid forums  for a few years but have not participated in them for a long time because I was engaged with a dissertation. I have now completed it.  

I can now begin the MP.  I have the drugs and a temporary set of disposable glasses ready to begin it at home.
 
What I want to know is if things are really starting to go awry.   Drugs the specialists give me seem to make no difference to the disease now.  I was originally diagnosed with sarc in 1999.
 
In August last year when taking 40mg of Plaquenil they discovered I had a raised ACE, ESR and my chest x-ray showed new activity.  They also found I had a helicobacter infection in the stomach. 
 
I have recently had a new set of tests done.  I was taken off Plaquenil and put onto Imuran because it seems that as well as sarcoid, I also have psoriasis with an arthritic component.
 
I believe my latest test results have sarcoidosis written all over them but I would like an expert opinion.  I will get and 25 D and 1-25 D done as soon as I can.

The most recent tests done 11/22 (fasting) showed this

* = abnormal

 

Biochem

 

Na      143 mmol/L  NR  (135 - 135 mmol/ L)

K         4.4 mmol/L   NR (3.5 - 5.6)

Cl        108 mmol/L  NR  (99 - 108)

HCO3   23 mmol/L   NR  (23 - 33)   (It would appear I am teetering on the edge of Acidosis)

 
 

Ca 2+ 2.44 mmol/L NR (2.10 - 2.60)

Ad Ca  2.44 mmol/L NR (2.10 - 2.60)

* Phos  1.43 mmol/L NR (0.80 - 1.40)

I know this is not greatly raised and my calcium is normal but I have had two non-traumatic tooth fractures this year and I have lost 2 cm in height.

I addition,  I have a heart arrythmia and tachycardia over 100 beats/min

 

Uric Acid 0.26 mmol/L NR (0.15 - 0.36)

Urea  3.7 mmol/L  NR (2.1 - 9.0)

Creat 65 mmol/L   NR (40 - 90)

 

 

Chol  4.0 mmol/L  NR  (3.9 - 5.5)

Trig   1.0 mmol/L  NR  (0.5 - 1.7)

 

Gluc   5.7 mmol/L NR ( 3.6 - 6.0)

 

 

LFTs

 

Bili  16 mmol/L  NR  (0 - 20)

ALP 53 U/L       NR  (30 - 115 )

* GGT 58 U/L    NR  (0 - 45)

LD 201 U/L        NR (100 - 225)

*AST  43 U/L     NR  (0 - 40)

ALT   39  U/L     NR  (0 - 40)

* T-Protein  57 g/ L  NR (60 - 80)

Alb            40 g/L  NR  (38 - 55)

*Globs      17 g/L  NR  (20 - 32)

 

 

eGFR  88 mL/min/1.73 M2

 

*ACE  77 U/L  NR (7 - 55)

 

*CRP  5.7  mg/L  NR (0 - 5)

 

ESR 20 mm/hr  NR  ( 0 - 28)  This range seems a little wide to me.

 

Full Blood Count

 

 

Hb   130 g/L   NR  ( 119 - 160)

WCC  * 3.8 x 10 9 / L   NR  ( 4.0 - 11.0)

Plats  352 x 10 9 / L     NR  ( 150- 450)

RCC   4.51 x 10 12 /L   NR ( 3.80 - 5.40 )

HCT   0.43 ratio            NR ( 0.34 - 0.47)

MCV   94.5 fL                NR ( 80.0 - 100.0)

MCH   28.8 pg              NR ( 27.0  - 32.0)

*MCHC  305 g/L           NR (310 - 360)

RDW  48.5  f/L              NR (35 - 50)

 

Neut          2.2 x 10 9/ L     NR (2.0 - 7.5)    56.7%

* Lymph    0.7 x  10 9 / L   NR (1.0 - 4.0)  *19.4%

Mono         0.5 x 10 9 / L    NR (0 - 1.0 )      14.2 %

Eosin         0.3 x 10 9 / L    NR (0 - 0.5 )        8.9 %

Baso         0.0  x 10 9 / L   NR  (0 - 0.3)         0. 8 %

 

I had a chest x-ray done Sept 2006.
 
It showed hilar lymphadenopathy and infiltrates  commensurate with sarcoidosis.  It was done at the same hospital where the biopsy and diagnosis was made in 1999.
 
The most recent one which I had done last week showed to be clear and suggested a CT Scan be done.  There was no lymphadenopathy but I think this private firm were trying to drum up business.

I will get the Ds done as soon as possible.   What stopped me doing the program before was the high cost of the Olmesarten.  I got it for nix and should only have to pay the minimum for it until I find a job. 

I have to have a halter monitor done for the heart.   I ECG said I had a qt prolongation.

Should I get the Ds done and begin MP or just start it?
 
How long should I leave between going off imuran and beginning the MP.
 
Den



____________________
MP stage2 Sarcoidosis,1999, reoccurence in lungs 2006, Psoriasis 1985, Psoriatic Arthritis 2006. ACE 108, 25D 7, CRP 5.2 Amytriptaline, Oroxine, Sumatriptan, Nexium
GeorgeinRollaMO
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 Posted: Wed Dec 12th, 2007 05:38

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Den,

Welcome!!!  :)

I am only an Advocate who can guide you around the websites.  The medical questions that you poise will have to be left to those with medical training to answer.

In the meantime, you might want to go over the MP Easy Finder & ABC of the MP

There really are a few things that you need to do/learn before starting the MP, which are classed as reading, reading, and some more reading.  :D  This is not a two-pills-twice-a-day-for-two-weeks type of protocol.   It is safe when done according to the guidelines, and other information that is available, mostly on the main site.

See 'Before You Begin The Marshall Protocol' and 'Links To Basic Information', which is at the top of the HOME page of the CureMyTh1 site.

You really do have to become your own advocate, and that takes some learning on your part.  ;)

Wishing you, and all, wellness!!!  :D

Dark Vader...aka, George

 



____________________
Borreliosis (but really Th1 inflammation). Start D values, July '04, 125D/57, 25D/61...over supplementation with D (fish oil).
Den
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 Posted: Sat Dec 15th, 2007 08:27

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Hi Dark Vader aka George,

Thanks for your help.

I despair of doctors.  I went to our local GP to cast feelers out to see if I could get any co-operation in order to get the Ds done.  But no dice.  This means I will have to wait until my main doctor reads my email and it will mean a 45 min trip into the city so that I can get her to write a request for vit D. 

This was because the FBC test he did in a tin-pot lab around the corner from my home was normal. 

I have no doubt what is going on.   I have a granuloma load evidenced by the raised ACE, leukopenia, lymphopenia, low ferritin level and raised CRP.  This is causing an imbalance in Calcium-phosphorus homeostasis which is causing the prolongation of the QT interval in the ECG and my teeth to fracture.   Next, it will be calcium deposits in soft tissue.   I have swelling of the feet of three weeks duration.  The doctor told me it was gravity. 

When I challenged his FBC results with the ones I had from the other lab he told me I must have had the flu.  His ECG was normal.   What was different from the first one I had?   The first one measured my height and weight, made me strip to the waist before attaching the electrodes and it was sent direct to the lab for a specialist to read.  The second one did the test with my underwire bra on and then took a cursory glance at it.

What planet are  they on!!!!!!!   God I hate doctors!!!!!!



____________________
MP stage2 Sarcoidosis,1999, reoccurence in lungs 2006, Psoriasis 1985, Psoriatic Arthritis 2006. ACE 108, 25D 7, CRP 5.2 Amytriptaline, Oroxine, Sumatriptan, Nexium
GeorgeinRollaMO
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 Posted: Sat Dec 15th, 2007 21:39

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Hi, Den,

I hear you!!!!  But thankfully, there are a few doctors that are scientists as well as being members of their guild.  It is just so hard to find those few!!!!  Most are very content to be part of the herd in whichever direction the stampede of the herd is headed.

It will be worth your while to find one of those brave and thinking scientifically-minded doctors.  Or, turn the head of one of those who you have more readily available to you.

But you will not be able to just walk into one of those doctor's offices and request they do the MP protocol with you.   You will need to find their Achilles tendon about doing the MP.  You will need to find what would turn the doctor onto doing the MP protocol, or, find out what is holding him/her back.   You will only do that by educating yourself very well about the MP pathogenesis (cause of the illness) or protocol (treatment of the illness).  You may even need to give the doctor that is wavering a 'release of liability' to relax him/her to do the MP protocol.  I did!!!!  Some day this may all change.    However, you may also be dead by then.  Which is the better route for you to go????

The doctor may feel that he/she is too busy to learn something new that might take lots of his/her time.  The doctor may or may not be impressed by the patient that can really speil off details about the MP pathogenesis and protocol.   If the doctor hears a lot of the "right stuff", the doc may be more willing to go along.

Do read the section on the HOME page of the 'study' site http://www.marshallprotocol.com  called "ESSENTIAL INFORMATION about the MP"  It is REQUIRED reading for you to do the official MP protocol and get needed Staff assistance while doing the MP protocol.   Also, REQUIRED reading is the section called "MARSHALL PROTOCOL FAQs"    You can read these without registering on the 'study' site, however, if you have not already done so, you might also register there... with the same name, if it is not already taken, etc.   You will need to be registered on the 'study' site to have your D-tests interpreted by Staff, and proceed on the MP protocol.

Two areas in which I have picked up that doctors are wary about.... are taking Benicar above the RDA [recommended daily amount] and so-called antibiotic resistance from taking abx for a long term.  

For the former, see the FDA Insert which can be found at http://tinyurl.com/auyfx which says that "Olmesartan shows linear pharmacokinetics following single oral doses of up to 320 mg..."   There are some very good reasons for using Benicar, and in greater amounts than the FDA RDA.  Which all means that for the FDA regularly approved use of Benicar to lower blood pressure 40 mg is sufficient, and any further dosage is just throwing money out of the window... but it is safe for our MP purposes at the MP recommended amounts.  There is a link for those other reasons for using Benicar but I will let you discover that section in your time. :)  

As to the latter wariness, see the link "Won't the bacteria become antibiotic resistant to long term use"

As I said previously, the patient has to be his/her own advocate!!!! :X

I took two and a half months of reading, reading and more reading on the MP websites before I started the MP protocol.   I know that you are in pain and want relief NOW.  But you are NOW heading in the correct direction.   One has to be patient while doing the MP.   I am now getting some very good results after three years.  :D

We, both, may have had a very high load of the L-forms!!!  :(

Wishing you, and all, wellness!!!  :)

Dark Vader...aka, George





____________________
Borreliosis (but really Th1 inflammation). Start D values, July '04, 125D/57, 25D/61...over supplementation with D (fish oil).
Martin78
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 Posted: Sat Dec 15th, 2007 22:05

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Hi Den

Why didnt they do Albumin when they were doing your calcium levels?

It should have been done, cal needs to be corrected for albumin levels.

Another thing:

You calcium levels should not differentiate more than 1,8% (!) Do you have previous test results to compare with?

Most GPs dont know anything about calcium metabolism. They see it within normal range and think everything is ok. Well, its wrong.

For example: If you have 2,44 in one test, and 2 days later 2,55 (presupposed same albumin level) your calcium metabolism is not right.

Symtoms like; constipation, heart palp, pricking fingers or facial externalities, depression, crying attacks, decal of teeth, "feeling of going crazy"....is typical calcium symptoms that can appear even if your level is within normal levels (not hyper of hypo calcimia) Its not only the level itself that is interesting, its the fluctuations in the level that causes the problems... a healthy body keeps its calcium levels within a very very very strict range. 

When the body sences to much or to little calcium the parathyroidea kicks in and your PTH is regulated within seconds to correct the calcium levels. If your GP dosent know this, well it should be quite easy to show him/her the litterature on the subject.

 You should see an endo. and let him meassure your PTH,  cal, ionised cal, albumin, 025 and 1,25 three times in a row, for example every week for 3 weeks. You should also deliver urine samples, that is where it is first shown.(excess calcium)

This way a potential dysreg. calcium metabolism will show clearly.

Show the endo's conclusion to your amateur GP, or even better; fire him/her. change doctor.

I can not belive that a doctor refuses to do D-levels for a patient already dx'ed with sarc... what kind of a country is the U.S, really? I know your forreign politics is extremely embarrising for you and that you are led by a very little inteligent guy, but geee.. I keep reading shock stories from the U.S here.

I'v had to fight against many doctors in Norway myself, and I am not saying our system is perfect by any means,  but atleast they let you run every test you ask for.... I have never been denied any blood, imaging or other test since I got sick.

Keep it up Den!

Martin



____________________
On Break|Sjøgrens Syndrome /Fatigue Wtloss Swallow|ancle legs/fingers/neck/shoulder/chest cardiac/itch/sweats/irrit/depres/insom/lymph| hypercal 10May07 25D=29 1,25D=98
28Aug07 25D=32 1,25D=74 http://www.youngsjogrens.com
GeorgeinRollaMO
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 Posted: Sat Dec 15th, 2007 22:21

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Den,

Martin has some very good points!   :)

However, remember that Dr. Marshall, Phd, has said that the 125D hormone is at the center of the control of ALL other hormones, which could be triggering all of the imbalance that tests show.   Treating each imbalance by itself may not be really productive.

I had about six hormones, by test, that were showing an imbalanced condition.  For one thing, my body temperature was mostly in the 97.X and even 96.X range at that time.  My doc wanted me to do some things that I considered "crazy", and I opted for the MP instead.  My body temperature is now mostly in the 98.X range today.

Wishing you, and all, wellness!!!  :)

Dark Vader...aka, George



____________________
Borreliosis (but really Th1 inflammation). Start D values, July '04, 125D/57, 25D/61...over supplementation with D (fish oil).
Den
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 Posted: Sun Dec 16th, 2007 02:30

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Hi Martin,

Thank you for you advice about Calcium metabolism.  I actually do have a good co-operative doctor who will supervise me on the protocol.  She is very hard to get into see.  Many of her patients are a lot sicker than I am.  She is a specialist general practioner whose books are closed and she only deals with complex medical problems.  I also have to travel 45 to 50 mins into Sydney to see her.  The doctor I saw the other day is within 5 mins walking distance from home, but I have seen him for the last time.  I will have to stick with this doctor if I am going to go on the protocol or find a new one.

I have been reading and I realise I will have to get PTH, urine calcium and serum calcium and albumin levels redone as well as the 25 D and 1-25 D.  This doctor is happy to go along with what I say.

I would love to see Norway some day.  My Mum has been there.   I lived in Scotland for a few months during Autumn and Winter.  I found it very good for my sarcoid symptoms.  I expect the opposite much be the case in summer when there is a lot of light. 

I have to put you straight on the US though.  I am from Downunder - Australia.  I have to admit our previous administration supported and copied many things done in the States but we have a new government and we have ratified Kyoto.  We still have a full medicare system in place.  As I am unemployed but looking after a sick mother I got my prescriptions (Olmetec and Minocycline) filled without cost.  I am ready to start once I have got these tests and more reading done.

With grateful thanks,

Den



____________________
MP stage2 Sarcoidosis,1999, reoccurence in lungs 2006, Psoriasis 1985, Psoriatic Arthritis 2006. ACE 108, 25D 7, CRP 5.2 Amytriptaline, Oroxine, Sumatriptan, Nexium
Den
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 Posted: Sun Dec 16th, 2007 02:36

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Thanks George,

I guess I will be doing a lot of reading in the next few weeks.

Den



____________________
MP stage2 Sarcoidosis,1999, reoccurence in lungs 2006, Psoriasis 1985, Psoriatic Arthritis 2006. ACE 108, 25D 7, CRP 5.2 Amytriptaline, Oroxine, Sumatriptan, Nexium
Den
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 Posted: Sun Dec 16th, 2007 03:12

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Hi again Martin,

I found some previous results from November last year - so just over a year a go.  I was still on prednisone at this stage.

 

14 Nov 2006

 

Calcium 2.42  Corrected calcium was 2.34,  Alb was 44.  Phos  1.37

22 Nov 2007

Calcium 2.44, Corrected calcium was 2.44   Alb was 40    Phos 1.43 (High)

all others within normal limits.

Is this of any use?

Den



____________________
MP stage2 Sarcoidosis,1999, reoccurence in lungs 2006, Psoriasis 1985, Psoriatic Arthritis 2006. ACE 108, 25D 7, CRP 5.2 Amytriptaline, Oroxine, Sumatriptan, Nexium
Dr Trevor Marshall
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 Posted: Sun Dec 16th, 2007 11:21

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Den,
I have asked Martin not to respond to questions asking for advice about medical issues. The moderators walk a very fine line when trying to evaluate data, as they can only look at a very small subset of the issues which that data might contain.

You must rely on your primary care physician to evaluate and advise you on what to do. There is a physicians' forum at the study site which you physician can join, and discuss the intricacies of such things. The nurses who moderate the study site also do their best, in conjunction with the physicain members, to help folk understand clinical issues.
 

Den
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 Posted: Tue Dec 18th, 2007 08:55

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I can appreciate your point and the fine line that you walk.  I can also appreciate that physicians may criticise the phorum for lay people giving out advice.

The only doctor I trust and can talk too and knows my history has just gone off on holidays and won't be back until the end of january.

We sent off a urine.   She gave me a request form to have 25, 1,25 Vit Ds, TFT, Calc, Phos, PTH and a few other things.  I took her a MSU which she dip stick tested and I had blood and 1+ protein.   She took my blood pressure and it nearly blew me away.  170/50.   I have pitting edema of the feet and ankles and I am really worried my kidneys are beginning to fail.   I believe you cannot take Benicar if your kidney's are not 100%.   Is that right?  What should I do?

Also if kidneys are OK,   Can I start Olmetec after I have had the Ds done but before the results come back?   I won't be able to get those results until Jan or until I can get into see either the endocrinologist or the kidney specialist.

Den



____________________
MP stage2 Sarcoidosis,1999, reoccurence in lungs 2006, Psoriasis 1985, Psoriatic Arthritis 2006. ACE 108, 25D 7, CRP 5.2 Amytriptaline, Oroxine, Sumatriptan, Nexium
Reenie
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 Posted: Tue Dec 18th, 2007 19:52

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Den,

Actually, Benicar is reno-protective as stated in this (filelink)
Kidney disease although your doctor may be unaware of this information.

Please be sure to start a new thread if you haven't already done so here, 
Preliminary test results (for Comment) with your new test results and you'll want to be sure the blood is frozen for the 1,25D test.

D-Metabolites Tests

Den
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 Posted: Wed Dec 19th, 2007 10:10

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Thanks Reenie,

I appreciate the help.  I have my Mum sick at the moment and am running errands for her during the day so the best I can do is print off a few things from these phorums to read at night in bed.

I am going to attend pathology at Concord Hospital.  They are supposed to be the best place in Sydney to get the D metabolites done.  I worked out today that I won't be able to do it until some time early in the new year.   It is a fair drive away.  I made appointments today to see a renal specialist (25/1) and an endocrinologist ( I think it is late Feb for him).

I am pretty well up to par digesting phase one of the protocol so once I get the Ds done I can get off the mark.     

I will be sure to read your links

Thank you

 



____________________
MP stage2 Sarcoidosis,1999, reoccurence in lungs 2006, Psoriasis 1985, Psoriatic Arthritis 2006. ACE 108, 25D 7, CRP 5.2 Amytriptaline, Oroxine, Sumatriptan, Nexium
Den
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 Posted: Thu Jan 10th, 2008 08:42

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Hi Reenie,

I had my D-Metabolites done at Concord Repat today.   I told them the that the 1-25 D had to be frozen.  I was led to believe by another MPer that Concord was the gold standard for 1,25 D in Sydney.   I have had them done 4 or 5 times there now and only one of the tests was meaningful.   In the others the 1.25 was so low that I suspect the specimen was not handled correctly.   I told them that they were probably confusing the 1.25 with the 25-OH.  They said that to their knowledge they never froze 1.25 D.   So I can expect another set of meaningless results.:(   I should have argued and said I am not leaving the collecting room until it is frozen.  They should have dry ice on hand.   I had a fight over this with another collector.  

It is not like I am an idiot.  I am a certified path tech myself and I used to send these unusual tests away to the teaching hospitals as per the manuals.  Blood Collectors and doctors used to ring and check with me what they needed  to do for less common blood tests and what tubes needed to be used.  Many people getting blood tested wouldn't know the difference between plasma and serum.  It is really difficult when the boot is on the other foot and your the patient.   These people assume patients don't know anything, but they could be taking blood from an MD.

 



____________________
MP stage2 Sarcoidosis,1999, reoccurence in lungs 2006, Psoriasis 1985, Psoriatic Arthritis 2006. ACE 108, 25D 7, CRP 5.2 Amytriptaline, Oroxine, Sumatriptan, Nexium
Den
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 Posted: Tue Jan 15th, 2008 22:38

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I now have both NoIRs, the DVDs and the Olmetec and Mino in the cupboard.

I am currently on a second lot of trimethoprim?? for a recurrent UTI.  I know I cannot begin the MP before finishing. (four days left)

Should I wait until my doctor comes back from holidays before beginning the olmetec?  She's back on 29/1.    I have developed a cardiac QT prolongation and peripheral oedema.

I am on unemployment benefit at present.  Would it be wise to get a certificate to cover me and exempt me from looking for work (that is if I don't get a job in the meantime) for the first couple of months where the extreme herxing occurs?  I get migraine, nausea and drunken co-ordination from hypervitaminosis d.  I have Heerfordt's syndrome too.  I believe some people have required medical attention herxing with arrythmia.

You know what would be really helpful?  Not everyone (if you have brain fog) retains what they read.  Some people are not wired that way and if they are sick they may have greater difficulties, particularly if they dont have an interested relation who can read the stuff for them and coach them along

When you get the MP streamlined (and I understand it will be tweaked depending on further research) it would be useful to put the MP first three months onto DVD.  Some people are visually oriented, still others learn better by auditory means.

Den



____________________
MP stage2 Sarcoidosis,1999, reoccurence in lungs 2006, Psoriasis 1985, Psoriatic Arthritis 2006. ACE 108, 25D 7, CRP 5.2 Amytriptaline, Oroxine, Sumatriptan, Nexium
Julia
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 Posted: Tue Jan 15th, 2008 23:22

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Den,

Most folks print out the Phase 1 guidelines and keep them handy to refer to.  Have you watched the LAX 2006 conference DVDs yet?  On Disc 2 Meg does a Phase 1 tutorial.

Your other questions will have to wait for someone better qualified :).

Julia 



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Always consult a physician
Essential Info; FAQ; Julia's story
Den
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 Posted: Tue Jan 15th, 2008 23:38

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Hi Julia,  I have already done both of those things.  I had a cursory look at the DVDs yesterday.  I didn't go to bed until after 1 a.m.    I must have missed Meg's tutorial.

I have a job interview today and then I have to sign on.   I will be free to take a look maybe, later this afternoon.

With thanks,

Denise



____________________
MP stage2 Sarcoidosis,1999, reoccurence in lungs 2006, Psoriasis 1985, Psoriatic Arthritis 2006. ACE 108, 25D 7, CRP 5.2 Amytriptaline, Oroxine, Sumatriptan, Nexium
Den
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 Posted: Fri Jan 25th, 2008 07:53

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Is is safe to take amytriptyline and proton pump inhibitors on MP?  I could not see them listed in contraindicated medications.

Also, I wondered about the relationship between ACE and high blood pressure in sarcoidosis.

When sarcoid is active I have large BP swings.  From High to low and back again. 

High BP does not seem to be a common symptom of sarcoid except where it precipitates pulmonary hypertension. 

I am sure the olmetec will help it.  Certainly the calcium channel blocker hasn't   I had slightly high BP on two occasions during the 13mths I was on prednisone.  However, it has become higher since I came off it last October but also drops to 100/70 and the pulse slows from over a hundred to mid thirties.

Is the high ACE in sarcoid causing too much Angiotensin I to be converted into Angiotensin II causing blood vessel constriction and therefore raising BP?

Do other people with sarcoid and CFS with high ACE levels get fits of high BP or is it unrelated?

I am starting phase 1 tomorrow.  I have had doctors right up to the back teeth. 

Tks a million  Denise 

 Tomorrow begins the rest of my life.   I believe it will be a little rocky at first but then I shall emerge from the sarcoidosis chrysalis a smaller, fitter and brighter person who can give, instead of taking from the world. (and don't they make you feel guilty about it).  It's time to fight back and take control.


 



____________________
MP stage2 Sarcoidosis,1999, reoccurence in lungs 2006, Psoriasis 1985, Psoriatic Arthritis 2006. ACE 108, 25D 7, CRP 5.2 Amytriptaline, Oroxine, Sumatriptan, Nexium
Julia
Advocate (on leave)


Joined: Wed Oct 17th, 2007
Location: Belfast, United Kingdom
Posts: 1338
Status:  Offline
 Posted: Fri Jan 25th, 2008 09:05

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Denise,

Please see Should I stop taking any of my medications?

I have insomnia and fatigue. What should I do?

Meg has said,

Proton pump inhibitors, like Protonix, are very effective at reducing acid reflux but they are officially recommended for short-term use. It's best to treat the underlying problem which you are doing with the MP. In the meantime, though, their palliative use is fine.


These links should help with some of your other questions:

Why is my B/P high? Why does it fluctuate?

Benicar Applications Beyond Hypertension


ACE test

Congratulations on reaching the starting line!  You might like to review these links:

Before You Begin the Marshall Protocol

Sarcoidosis Facts

MARSHALL PROTOCOL FAQs (Required Reading)

Are you wearing your NoIRs and cutting out daylight in your home? 

When you start taking Benicar, you must start a progress report in the Benicar only forum.  After that, please ask all medical and lifestyle questions in your progress report.

You will still be welcome to post here in your own thread, if you have non-medical questions such as "how do folks cope with colleagues who don't understand?" or "did anyone else have this symptom?" or just to get a bit of sympathy when the going gets tough (it will :X).  And as you've gathered, we're good at finding the information you're looking for in the labyrinth of the main site!  But all medical and lifestyle questions will be part of your progress report.

I like your chrysalis analogy.  Happy herxing!

Julia 



____________________
Always consult a physician
Essential Info; FAQ; Julia's story
Den
Member
 

Joined: Tue Dec 11th, 2007
Location: Sydney, Australia
Posts: 16
Status:  Offline
 Posted: Wed Jul 23rd, 2008 12:17

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Hi,

I have a new question regarding the cellular biochemistry. 

I understand that when bacteria die and release endotoxins, a lot of NO is produced.  Is superoxide also produced?  Does it effect the cells' mitochondria?  Do mitochondria in other cells shut down in order to survive?  Is this the source of fatigue during herxing? 

Den



____________________
MP stage2 Sarcoidosis,1999, reoccurence in lungs 2006, Psoriasis 1985, Psoriatic Arthritis 2006. ACE 108, 25D 7, CRP 5.2 Amytriptaline, Oroxine, Sumatriptan, Nexium

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